Pain and Anaesthesia Research Centre


At Barts Health NHS Trust

PARC

 

Research

Current studies

Qutenza, quantitative sensory testing, spinal cord stimulation and percutaneous electrical nerve stimulation


This study is evaluating changes in central and peripheral sensitisation with neuromodulation.

ReActiv8-A


A randomised sham controlled study to investigate multifidus stimulation for patients with low back pain.  Barts Health NHS Trust is one of very few worldwide centres to be recruiting for a study to evaluate multifidus muscle stimulation as a novel therapy for chronic low back pain management.


For more information, please click here

High frequency PET scan study (Boston)


A single blind, crossover pilot study investigating dynamic brain imaging responses to different frequency parameters (40Hz, 4000Hz and 10000Hz) of spinal cord stimulation in participants with intractable lumbar neuropathic pain.

Greater occipital nerve blocks and chronic migraine


This portfolio CLRN study is a single-blinded randomised placebo controlled crossover trial to assess the efficacy of greater occipital nerve block injections with steroid and normal saline in participants with chronic migraine.

Medtronic


An open label, pilot study investigating the changes to different high density frequency parameters and variable electrode array responses on the Medtronic restore sensor technology.  This is tested in participants with intractable lumbar neuropathic pain who have not undergone previous spinal surgery.

Nalu


A European, multicentre open label, feasibility study investigating the safety and efficacy of the Nalu external trial stimulator in participants with neuropathic pain via spinal cord stimulation.

Boston Virgin Back


A pilot study investigating the response to 1000Hz high frequency stimulation in participants with intractable neuropathic pain who have not undergone spinal surgery.

Contour


A randomised controlled study investigating the response to different programmed settings of 1000Hz frequency spinal cord stimulation in participants with neuropathic pain.

Velocity


A multicentre study characterising real world outcomes of high rate spinal cord stimulation.

ReActiv8-B


A double blinded, randomised sham controlled study of an implantable stimulator.


RELIEF - a global registry to evaluate long-term effectiveness of neurostimulation therapy for pain


A three-year worldwide registry to evaluate longterm outcome data on 6000 patients with spinal cord stimulation.  The purpose of the study is to compile characteristics of real-world clinical outcomes for Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice, when used according to the applicable Directions for Use, and to evaluate the economic value and technical performance of Boston Scientific commercially approved neurostimulation systems for pain in routine clinical practice.


For more information, please click here